Tunable delayed controlled release profile from layered polymeric microparticles
نویسندگان
چکیده
منابع مشابه
Mechanisms of burst release from pH-responsive polymeric microparticles.
OBJECTIVES Microencapsulation of drugs into preformed polymers is commonly achieved through solvent evaporation techniques or spray drying. We compared these encapsulation methods in terms of controlled drug release properties of prepared microparticles and investigated the underlying mechanisms responsible for the 'burst release' effect. METHODS Using two different pH-responsive polymers wit...
متن کاملPolymeric ocular nanosuspension for controlled release of acyclovir: in vitro release and ocular distribution
The aim of this study is to formulate a novel ophthalmic nanosuspension (ONS), an alternative carrier system to traditional colloidal carriers for controlled release (CR) of acyclovir (ACV). In the present study, ONS is employed to avoid some of major disadvantages of colloidal carriers systems such as instability in cul de sac and short half life by increasing efficiency of drug encapsulation ...
متن کاملPolymeric ocular nanosuspension for controlled release of acyclovir: in vitro release and ocular distribution
The aim of this study is to formulate a novel ophthalmic nanosuspension (ONS), an alternative carrier system to traditional colloidal carriers for controlled release (CR) of acyclovir (ACV). In the present study, ONS is employed to avoid some of major disadvantages of colloidal carriers systems such as instability in cul de sac and short half life by increasing efficiency of drug encapsulation ...
متن کاملThermally induced release from polymeric microparticles with liquid core: the mechanism.
Herein we demonstrate how the volatility of a liquid can be manipulated by enclosing microdroplets of the liquid into thin polymeric shells. In this way, composite core-shell microparticles consisting of 80 wt% of a liquid core material and 20 wt% of a polymer can be made 150 °C more stable than the individual core component. The thermal stability of the composite microparticles is found to be ...
متن کاملNonlinearities in Drug Release Process from Polymeric Microparticles: Long-Time-Scale Behaviour
1 Department of Natural and Synthetic Polymers, Faculty of Chemical Engineering and Environmental Protection, “Gheorghe Asachi” Technical University of Iasi, Prof. Dr. Docent Dimitrie Mangeron Road, No. 73, 700050 Iasi, Romania 2 Department of Physics, Faculty of Machine Manufacturing and Industrial Management, “Gheorghe Asachi” Technical University of Iasi, Prof. Dr. Docent Dimitrie Mangeron R...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Materials Chemistry B
سال: 2017
ISSN: 2050-750X,2050-7518
DOI: 10.1039/c7tb00138j